PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pp3c16_2870V3.3.p
Common NamePAN3, PHYPADRAFT_170356
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella
Family C3H
Protein Properties Length: 1153aa    MW: 124175 Da    PI: 7.1254
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pp3c16_2870V3.3.pgenomeCOSMOSSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH309.1e-101436527
                       --SGGGGTS--TTTTT-SS-SSS CS
            zf-CCCH  5 lCrffartGtCkyGdrCkFaHgp 27
                        Cr++a +GtC +Gd+C+FaH p
  Pp3c16_2870V3.3.p 14 TCRYWATSGTCFFGDQCNFAHNP 36
                       6********************85 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5010314.68937IPR000571Zinc finger, CCCH-type
SMARTSM003568.9E-51136IPR000571Zinc finger, CCCH-type
SuperFamilySSF902291.83E-61238IPR000571Zinc finger, CCCH-type
PfamPF006427.9E-71436IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.108.6E-81538IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010310.3524776IPR000571Zinc finger, CCCH-type
SMARTSM003566.34975IPR000571Zinc finger, CCCH-type
HamapMF_0318124.5955301122IPR030844PAB-dependent poly(A)-specific ribonuclease subunit PAN3
Gene3DG3DSA:3.30.200.202.2E-8552614No hitNo description
Gene3DG3DSA:3.30.200.202.2E-8740885No hitNo description
PROSITE profilePS500119.3337441051IPR000719Protein kinase domain
SuperFamilySSF561124.6E-12760973IPR011009Protein kinase-like domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000289Biological Processnuclear-transcribed mRNA poly(A) tail shortening
GO:0006397Biological ProcessmRNA processing
GO:0006468Biological Processprotein phosphorylation
GO:0031251Cellular ComponentPAN complex
GO:0004672Molecular Functionprotein kinase activity
GO:0005524Molecular FunctionATP binding
GO:0044822Molecular Functionpoly(A) RNA binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000006anatomyplant protoplast
PO:0025017anatomyplant spore
PO:0030003anatomyprotonema
PO:0030018anatomygametophore
Sequence ? help Back to Top
Protein Sequence    Length: 1153 aa     Download sequence    Send to blast
MSVSPQKPPV SNVTCRYWAT SGTCFFGDQC NFAHNPADRA ATGKSVPKRE KACKELLLTG  60
YCKNEKNGCE YNHEIPGVIR AGPPASSTTA ANVSTSVVYS SWSSTASSSL SSGAVAAIRN  120
HRLPVSAPAF VPAAVAAAQR ASLSAWGGVT PGKCVAVTSQ ATSTTISTTQ NDSLSVSSGQ  180
TSVVDTQTTS APGSLVEEAE VSGNPDTISS GISVSTSLSS FSNSLLNAQP FIPSISSAIS  240
GSLNGPSPPY SGTTQGASVG SANATPFVPS GGSVASAVSA VPFVPRSRQH LVTGATTGGG  300
SSGMGWALQP VSSSLMALGG PAPQQQLQIR QHQLSQLQQQ IQQQVAAQAQ VQAQLQAQVQ  360
AQAQAQAHML AAAARGISGS VLSNNQYMGM DMPTVLPSFR LPDGDDPALG MTAMSPPNPS  420
FSTRAQLLQH MQNMQLQQQH QAFSGQSSPY SLRSLQRTGA QTPEKQQQLL NSQSEQQSQS  480
PPYAIWLSQS LGTHTPEKSQ PLALKADAGG SVSSSLALSN DNQVQEHVLP STPERRESDQ  540
LSVQSLEHIG PPQSPQQTGQ IQSPQQQPTA VSQSSTKQQQ QAQIQHQIQL QALQQQRMRH  600
RMQQQQQQQQ QQQHFQQGQR VLTGTGLTQQ RLPSVRSPSP ISGSSPVAAA THGGATYFLG  660
PGQGISSLSH AFSSPVGRNE SRTARSQFPA GTVPFGSRFL PDQLREELRR RHSLIHAQLD  720
PEQDLVDLPE MVQRFHSLYP LEDVNREDEI PSASFGVRTM LFKGISSSDG QAYAIRRIDS  780
HQVIPTAELA NTAVEVVERW APFARHPHIV AIRESFVSRE VEDSAALFFV HDYYPAALTL  840
QAIHLQQEQP SGVVHLTVNE EQLWSYMVQL ATVLRAVHSA GLYFRPGGLH PSKVILTSKG  900
RIRVSGVGIL DVLHGDPSDD PRMFQREDLA GCGRLILALA CGSTANASLE FMGSHYSADL  960
VRITQALLAS SPEKSEGAGI CSIRQLCSAL ADRMFNEIEN VHMQNDENLN ELSKETENGR  1020
LLRILVKLGM INERPEHDMD PAWSEIGDRY LLKLFRDSVF HQTSEEGTPV IDWGHVVECL  1080
NKLDAGVPEK LILLSRDERS MLIASYADLK RCLENVYQEL LVRASGDKAR QAPPQNMLMQ  1140
SPVRLSQRLH VI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4bwp_A2e-7470011267448PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE S
4bwp_B2e-7470011267448PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE S
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ppa.113930.0protonema
Functional Description ? help Back to Top
Source Description
UniProtRegulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with PABP. {ECO:0000256|HAMAP-Rule:MF_03181}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_001778619.10.0predicted protein
TrEMBLA9TJ350.0A9TJ35_PHYPA; PAB-dependent poly(A)-specific ribonuclease subunit PAN3
STRINGPP1S242_6V6.10.0(Physcomitrella patens)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G12680.14e-06floral homeotic protein (HUA1)
Publications ? help Back to Top
  1. Rensing SA, et al.
    The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants.
    Science, 2008. 319(5859): p. 64-9
    [PMID:18079367]